Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking apixaban and each time you get a refill. If you have any of the symptoms listed above, contact your doctor or go to a hospital right away. Refill your prescription before you run out. You may also experience a fever, with your skin feeling hot to the touch. Taking a blood thinner as part of your AFib treatment can reduce your risk of blood clots and stroke. If you have any planned surgical, medical, or dental procedures, your doctor may recommend stopping Eliquis to reduce the risk of bleeding. In clinical trials, side effects of Eliquis in older adults were similar to those in younger adults. For example, you may consider: Additionally, you should tell any healthcare professionals who treat you that youre taking Eliquis. Do not stop taking it any earlier unless you have discussed it with your doctor first. My doctor prescribed ELIQUIS (apixaban) for: To Reduce Stroke Risk Due to AFib Not Caused by a Heart Valve Problem. See the drugs prescribing information for details. (2020). Curious about drug rashes and what they look like? Discuss this with your doctor. Canada residents can call a provincial poison control center. They can tell you if and when you should stop Eliquis and when to start taking it again. The dosage is based on your medical condition, age, weight, kidney function, response to treatment, and other medications you may be taking. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks side effects of the medication. Clopidogrel is used to prevent heart attacks and strokes in persons with heart disease (recent heart attack ), recent stroke, or blood circulation disease (peripheral vascular disease).It is also . If this side effect is severe or bothersome to you, your doctor may be able to recommend ways to help prevent it. Last medically reviewed on September 22, 2021. If you have a spinal procedure while taking Eliquis, you may have a higher risk of spinal blood clots if you: Symptoms of a spinal blood clot may include: If you need to have a spinal procedure while taking Eliquis, make sure your doctor knows that youre taking this medication. Mild side effects that have been reported with Eliquis include: bruising. Active bleeding. If youve had an allergic reaction to Eliquis or any of its ingredients, your doctor will likely not prescribe Eliquis. See below for more important safety information about ELIQUIS. If any of these effects last or get worse, tell your doctor or pharmacist promptly. In clinical trials, some people taking Eliquis reported having blood in their urine, which could be a sign of bleeding in the kidneys. What are the possible serious side effects of ELIQUIS? Eliquis hasnt been reported to cause kidney-related side effects, such as kidney damage or reduced kidney function. Learn more about some of the side effects Eliquis may cause. hives, itching, skin rash joint pain or swelling nausea and vomiting nosebleeds puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue redness of the eye severe stomach pain shortness of breath tightness in the chest unusual tiredness or weakness vomiting of blood or material that looks like coffee grounds Warfarin is an anticoagulant medicine (blood thinner). The affected skin may be sensitive or painful, and severe cases can result in oozing sores, cracked skin or bleeding. However, its always a good idea to talk with a doctor about any drug rashes as well as before you stop taking any particular medication. Learn more. Learn about the side effects and safety measures, For self-administered medications such as Eliquis, Medicare has two coverage options: Medicare Part D and the Medicare Advantage Plan. An active ingredient is what makes a drug work. But if you have any symptoms that are ongoing or bother you, talk with your doctor or pharmacist. There arent any known interactions between Eliquis and alcohol. But alcohol can increase your risk of bleeding. The phase IV clinical study analyzes which people take Eliquis and have Rashes. If you have a severe liver problem, your doctor will likely not prescribe Eliquis. The two companies were testing Eliquis, which includes apixaban, an orally-taken inhibitor which blocks a key blood-clotting protein, reducing the risk of thrombin generation and blood clots. 1 / 2 Look up another drug Find other drugs that treat. Take ELIQUIS exactly as prescribed by your doctor. Is exercise more effective than medication for depression and anxiety? You may hear this medication referred to as a blood thinner. If youve had a heart valve replacement, your doctor will likely not prescribe Eliquis. If youd like to notify the FDA about a side effect youve had with Eliquis, visit MedWatch. If youre concerned about kidney-related side effects occurring during Eliquis treatment, talk with your doctor or pharmacist. Warfarin-induced skin necrosis refers to a rare condition in which there is paradoxical blood clotting. Otherwise, call a poison control center right away. However, your risk of this reaction tends to be higher at the start of taking a very high dose of a new blood thinner. Your doctor can help determine the cause and can also give advice on remedies or treatments. Eliquis has boxed warnings for the risk of blood clots if stopping Eliquis treatment early and risk of spinal blood clots from certain spinal procedures. Find out how to know if you have one and what to do about it. Your doctor will tell you when you should stop taking ELIQUIS and when you may start taking it again. If needed, your doctor may give you an antidote to reverse the effects of Eliquis, for example if the medication causes serious bleeding. This drug may not be the right treatment for you if you have certain medical conditions or other factors that affect your health. Take your next dose at the regular time. We explain the connection between blood clots and flying, tips for prevention, and what you should know if you have a history of this condition. Artificial heart valve. For example, being less mobile raises your risk of deep vein thrombosis, which Eliquis is used to treat and prevent. None of it's unbearable (yet). Does Eliquis interact with other medications? Activation and first use of the Co-pay. Eliquis comes as a tablet that you swallow, and its active ingredient is apixaban. Having certain medical conditions may increase the risk of side effects from taking Eliquis. Examples of the blood clots Eliquis treats include deep vein thrombosis (DVT) and pulmonary embolism (PE). This medication can cause serious bleeding if it affects your blood clotting proteins too much. Depending on what youre using Eliquis for, you may take it short term or long term. Heart failure: Could a low sodium diet sometimes do more harm than good? Possible causes of urticarial drug rashes include: Photosensitivity refers to reactions worsened by sun exposure. Bristol Myers Squibb reserves the right to rescind, revoke, or amend the Program without notice. Learn more. ELIQUIS can cause bleeding, which can be serious, and rarely may lead to death. A lumbar puncture is a procedure where fluid is collected from your spinal cord. Artificial heart valve. ELIQUIS and the ELIQUIS logo are trademarks of Bristol-Myers Squibb Company. You are encouraged to report negative side effects of prescription drugs to the FDA. Be sure to talk with your doctor about your health history before you take Eliquis. This could raise your risk of side effects. Besides talking with your doctor, you can do some research on your own. This list doesnt include all possible mild side effects of the drug. I was changed to Xarelto and the condition worsened and spread. For this reason,your doctor will likely not prescribe Eliquis. While taking ELIQUIS, you may bruise more easily and it may take longer than usual for any bleeding to stop. Certain drugs can make your skin extra sensitive to ultraviolet light, causing a subsequent itchy sunburn if you go outside without wearing sunscreen and protective clothing. However, if your symptoms seem life threatening, call 911 or your local emergency number immediately. Learn more about blood clot. hopkinsmedicine.org/healthlibrary/conditions/dermatology/drug_rashes_85,P00280, ejinme.com/article/S0953-6205(15)00414-8/fulltext, aaaai.org/tools-for-the-public/conditions-library/allergies/medications-and-drug-allergic-reactions, fda.gov/drugs/resourcesforyou/specialfeatures/ucm464195.htm, How to Recognize and Get Help for Hypersensitivity Syndrome, Overview of Purpuric Rash, a Symptom of Some Conditions, Debra Sullivan, Ph.D., MSN, R.N., CNE, COI, How to Get Rid of Dark Circles Permanently, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT. Some drug rashes are severe and require emergency medical treatment. Bleeding in this area can cause paralysis that lasts a long time or could become permanent. Learn more about the risk of developing an epidural blood clot while taking ELIQUIS. There are many possible triggers of these digestive problems. Also, if you take Eliquis to help prevent blood clots after hip or knee replacement surgery, you may have reduced mobility both before and after the surgery. They can become very itchy. Call your doctor for medical advice about side effects. Drug rashes can appear as a variety of skin rashes, including pink to red bumps, hives, blisters, red patches, pus-filled bumps (pustules), or sensitivity to sunlight. In some cases, they may recommend a different medication. For example, you may have internal bleeding in your digestive system, lungs, brain, liver, kidneys, abdominal cavity, joints, or eyes. If you drink alcohol, talk with your doctor about how much may be safe to consume while youre taking Eliquis. Tell your doctor right away if you notice symptoms such as back pain, leg numbness/tingling/weakness, loss of control of the bowels or bladder (incontinence). What does Eliquis look like? Note: Images do not represent actual tablet size. Eliquis and Rashes - a phase IV clinical study of FDA data Summary: Rashes is found among people who take Eliquis, especially for people who are female, 60+ old, have been taking the drug for < 1 month. Tell your healthcare team about all the medicines you take, including any: During treatment, make sure you talk to your healthcare team before you begin to take any newmedication. Don't soak the rash, but rinse it gently and pat it dry with a clean, dry towel. Your doctor or healthcare provider will determine what dose is right for you. Do not store in the bathroom. This clot may press on your spinal cord, which could cause long lasting or even permanent paralysis. If you have kidney problems, your doctor may recommend a lower dose of Eliquis for you. This will help them determine if Eliquis may be a safe treatment option for you. To use Elise, please try going to this website on a phone, tablet, or another internet browser, such as Chrome, Firefox, or Safari. Cellulitis Symptoms. Talk with your doctor if youre concerned about kidney-related side effects with Eliquis. If youd like to learn more about Eliquis, talk with your doctor or pharmacist. Who is at risk for AFib not caused by a heart valve problem? Radiation and chemotherapy for cancer are also possible causes. hives, itching, skin rash joint pain or swelling nausea and vomiting nosebleeds puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue redness of the eye severe stomach pain shortness of breath tightness in the chest unusual tiredness or weakness vomiting of blood or material that looks like coffee grounds Ask your doctor what other medications may be better options for you. The conditions and factors to consider include: Allergic reaction. I still have the itching rash, front and back, from ears to ankles. Kidney problems. This rash may develop suddenly or within hours, but it can take up to several weeks in some cases. If the side effects seem life threatening or you think youre having a medical emergency, immediately call 911 or your local emergency number. This drug has two boxed warnings. However, these side effects werent reported in clinical trials of Eliquis. Triple-positive antiphospholipid syndrome (APS). If it is near the time of the next dose, skip the missed dose. Spinal procedures include lumbar punctures (spinal taps), spinal injections, and epidural injections. The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a healthcare provider. Try wearing loose clothing and reducing skin-to-skin friction in affected areas. All rights reserved. Eliquis may not be right for you if you have certain medical conditions. People with triple-positive APS may have an increased risk of blood clots from Eliquis. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. This product may contain inactive ingredients, which can cause allergic reactions or other problems. If you have a bleeding problem or take other medications that can affect blood clotting, talk with your doctor about whether Eliquis is right for you. If you have a spinal blood clot, your doctor will give you medication to treat this as soon as possible. Eliquis can build up in your body if your liver isnt working properly. To learn more, see the Side effects explained section above. However, older adults may be more likely to have conditions that can raise the risk of side effects with Eliquis. If you do need to stop treatment with Eliquis, your doctor may recommend that you take a different blood thinner. Periorbital cellulitis is cellulitis by the eye. You may have nosebleeds during your treatment with Eliquis. [Text HELP to 69108 for help.] About 1% of patients have allergic or hematologic adverse reactions to clopidogrel. If you do need to suddenly stop taking Eliquis, your doctor may suggest a different medication for your condition. Adverse drug reactions and organ damage: The skin. Talk to your healthcare team about the following: Tell your doctor if you are pregnant or breastfeeding, or planning to become pregnant or breastfeed. All rights reserved. Talk to your pharmacist for more details. If you fall or injure yourself, especially if you hit your head, contact your doctor right away. Side effects of Eliquis typically get better after you stop taking the medication. If you have a nosebleed, pinch the top of your nose tightly for 10 minutes to help stop the bleeding. Before taking apixaban, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. ELIQUIS is a prescription medicine used to treat blood clots in the veins of your legs (deep vein thrombosis) or lungs (pulmonary embolism), and reduce the risk of them occurring again. The Food and Drug Administration (FDA) has approved it to treat and help prevent certain dangerous blood clots. Examples of mild side effects that have been reported with Eliquis include: In most cases, these side effects should be temporary. You may have a higher risk of bleeding if you take ELIQUIS and take other medicines that increase your risk of bleeding, such as aspirin, nonsteroidal anti-inflammatory drugs (called NSAIDs), warfarin (COUMADIN), heparin, selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs), and other medicines to help prevent or treat blood clots. To learn more, you can refer to Eliquiss prescribing information. Petechiae are tiny purple, red, or brown spots on the skin. If you are crushing the tablet and mixing it as directed in water, apple juice, or applesauce, use the mixture within 4 hours of preparing it. Theyll likely recommend a medication other than Eliquis for your condition. Drug-induced hypersensitivity syndrome (DIHS) is a rare, severe reaction to a medication. However, its possible you may gain weight due to the reason youre taking Eliquis. However, drinking large amounts of alcohol may raise your risk of bleeding with Eliquis. Your doctor will monitor you for symptoms of spinal blood clots after the procedure. Examples include certain azole antifungals (such as itraconazole, ketoconazole, posaconazole), conivaptan, HIV protease inhibitors (such as lopinavir), rifamycins (such as rifabutin), ritonavir, St. John's wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others. Message and data rates may apply. Introduction: Rivaroxaban is a novel oral anticoagulant with several indications, one of which is for stroke prevention in nonvalvular atrial fibrillation. You should continue taking Eliquis for as long as your doctor recommends. They alert doctors and patients about drug effects that may be dangerous. If you need Adobe Reader, click the link below to download the free readerLink to Adobe Reader Download page. Tell your doctor if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. Eliquis works by reducing your bloods ability to form clots. Eliquis comes with several warnings, which may affect whether the drug is a good treatment for your condition. Dont stop taking Eliquis without first talking with your doctor. If you have any bleeding thats severe or wont stop, call your doctor right away. For example, if the rash is very itchy, an antihistamine or oral steroid can help manage the itching until the rash clears up. They can recommend ways to maintain a healthy weight. This medicine is a pink, oval, film-coated, tablet imprinted with "894" and "5". A drug allergy is an allergic reaction to a medication. For people taking ELIQUIS (apixaban) for atrial fibrillation: Do not stop taking ELIQUIS without talking to the doctor who prescribed it for you. While any drug can cause a rash, certain types are more notorious for causing reactions. Its not known if Eliquis may be present in breast milk or may have an effect on a child who is breastfed. Symptoms of blood clots in your spine include: Before having any spinal procedures done, tell your doctor that youre taking Eliquis. Diarrhea has also been reported with a different type of blood thinner called Jantoven (warfarin). Please see U.S. Full Prescribing Information, including Boxed WARNINGS and Medication Guide. For more information, see the Warnings for Eliquis section below. Purpose: A case of a patient who developed a hypersensitivity reaction to rivaroxaban in the form of a diffuse, exanthematous rash is reported. If you have liver problems, Eliquis may build up in your body. A boxed warning is a serious warning from the Food and Drug Administration (FDA). This site is intended for U.S. residents 18 years of age or older. Its a prescription drug used in adults to prevent or treat blood clots in certain situations. They may suggest a treatment to manage your symptoms. Take this medication by mouth with or without food as directed by your doctor, usually twice daily (every 12 hours). Your risk of developing a spinal or epidural blood clot is higher if: a thin tube called an epidural catheter is placed in your back to give you certain medicine, you take NSAIDs or a medicine to prevent blood from clotting, you have a history of difficult or repeated epidural or spinal punctures, you have a history of problems with your spine or have had surgery on your spine. I've been on Apixaban for a 2 or 3 of years and over the last year I've started to have skin problems. What is the latest research on the form of cancer Jimmy Carter has? Tip your head forward and breathe through your mouth while doing so. While taking ELIQUIS, you may bruise more easily and it may take longer than usual for any bleeding to stop. Our website services, content, and products are for informational purposes only. If you have questions about your risk of side effects from Eliquis, ask your doctor. Having certain spinal procedures during Eliquis treatment may increase the risk of blood clots in your spine. Eliquis (apixaban) is a brand-name prescription medication. 4. Specifically, Eliquis is approved for use in adults to: Depending on the reason for taking Eliquis, you may take it short term or long term. Be sure to seek medical attention right away if you have signs or symptoms of bleeding such as unexpected bleeding or bleeding that lasts a long time. You shouldnt stop taking Eliquis suddenly without talking with your doctor. If you miss a dose, take it as soon as you remember. In Canada - Call your doctor for medical advice about side effects. But kidney-related side effects were not commonly reported in studies of the drug. Be sure to tell them right away if you have any of the symptoms listed above. Because of the possible risk to the infant, breast-feeding while using this drug is not recommended. This medication can cause bleeding. To learn more about this, see Side effect specifics below. If you notice blood in your urine, or you have pink or red urine while taking Eliquis, see your doctor right away or call 911 or your local emergency number. This may include bleeding in organs such as the kidneys. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, List Eliquis side effects by likelihood and severity. First a patch on my foot that appeared to be ringworm and did actually respond to ringworm creams, but did not clear up and is still here. However, if you have a spinal procedure such as a lumbar puncture (spinal tap) or epidural injection while taking Eliquis, it could cause a spinal or epidural hematoma (blood clot in your spine). Enter your medication into the WebMD interaction checker, deep vein thrombosis prevention in knee replacement, deep vein thrombosis prevention in hip surgery, treatment to prevent blood clots in chronic atrial fibrillation, blood clot in a deep vein of the extremities, blood clots with heparin-induced low platelet levels in the blood, prevention of venous thromboembolism recurrence, thrombosis with thrombocytopenia syndrome, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. If you have any active bleeding, such as a bleeding stomach ulcer, your doctor will likely not prescribe Eliquis. Many people using this medication do not have serious side effects. Use this medication regularly to get the most benefit from it. The products discussed herein may have different product labeling in different countries. Eliquis 5 mg tablet Color: pink Shape: oval Imprint: 894 5 This medicine is a pink, oval, film-coated, tablet imprinted with "894" and "5". This medication can increase your risk of bleeding. What should I know regarding pregnancy, nursing and administering Eliquis to children or the elderly. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Bleeding problems. Eliquis has a boxed warning for this side effect. Please see U.S. Full Prescribing Information, including Boxed WARNINGS and MedicationGuide. * And if you have atrial fibrillation, stopping Eliquis can raise your risk of having a stroke. If left untreated, a blood clot can reach your organs and cause potentially life threatening conditions, such as pulmonary embolism, stroke, or a. For more information, see the Side effect specifics section above.